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Effect of temperature on the high-performance liquid chromatographic separation of the anti-HIV agents, didanosine and stavudine

✍ Scribed by Frank A. Stancato; Nuggehally R. Srinivas; Catherine A. Knupp

Publisher: John Wiley and Sons
Year: 1996
Tongue: English
Weight: 204 KB
Volume: 10
Category: Article
ISSN: 0269-3879
DOI: 10.1002/(sici)1099-0801(199601)10:1<29::aid-bmc543>3.0.co;2-w

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✦ Synopsis

This paper examines the effect of temperature on the chromatographic separation characteristics of anti-HIV agents, didanosine and stavudine. As a result of lowering the column temperature, an improved resolution between didanosine and stavudine peaks is observed. Thus, lower temperatures may permit the simultaneous monitoring of didanosine and stavudine levels.

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