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Statistically significant meta-analyses of clinical trials have modest credibility and inflated effects

โœ Scribed by Tiago V. Pereira; John P.A. Ioannidis


Book ID
116623906
Publisher
Elsevier Science
Year
2011
Tongue
English
Weight
287 KB
Volume
64
Category
Article
ISSN
0895-4356

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โœ Bartolucci, Al ๐Ÿ“‚ Article ๐Ÿ“… 1999 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 45 KB ๐Ÿ‘ 2 views

Much of the literature is turning attention to metaanalyses. This may be positive in light of the many underpowered studies that have been reported. However, one must step back and put this activity in perspective and not lose sight of the important role of the clinical trial in research. Further e