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Statistical evaluation of alternative models: Application to ligand-protein binding

✍ Scribed by Estel D. Sprague; C.E. Larrabee Jr.; H.B. Halsall

Publisher: Elsevier Science
Year: 1980
Tongue: English
Weight: 487 KB
Volume: 101
Category: Article
ISSN: 0003-2697
DOI: 10.1016/0003-2697(80)90057-3

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✦ Synopsis

A new statistical procedure is described which permits the direct, quantitative comparison of alternative physical models for a set of experimental results. Its reliability is demonstrated through a computer simulation study, and its usefulness is illustrated in the analysis of nonlinear van? Hoff and Arrhenius plots for selected cases of steroidprotein binding and enzyme catalysis.

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