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Statistical Analysis of the Bioassay of Continuous Carcinogens

โœ Scribed by Paige, W S; Peto, Richard; Lee, P N


Book ID
109833174
Publisher
Nature Publishing Group
Year
1972
Tongue
English
Weight
558 KB
Volume
26
Category
Article
ISSN
0007-0920

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A stochastic model is proposed to describe time-dependent lethal effects of toxic compounds. It is based on simple mechanistic assumptions and provides a measure for the toxicity of a chemical compound, the so-called killing rate. The killing rate seems a promising alternative for the LC50. The mode