𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Statistical analysis of bioassays, based on hazard modelling

✍ Scribed by J. J. M. Bedaux; S. A. L. M. Kooijman

Publisher
Springer
Year
1994
Tongue
English
Weight
689 KB
Volume
1
Category
Article
ISSN
1352-8505

No coin nor oath required. For personal study only.

✦ Synopsis

A stochastic model is proposed to describe time-dependent lethal effects of toxic compounds. It is based on simple mechanistic assumptions and provides a measure for the toxicity of a chemical compound, the so-called killing rate. The killing rate seems a promising alternative for the LC50. The model also provides the no-effect level and the LC50, both as a function of exposure time ~. The model is applied to real data and to simulated data.

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