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Statin induced angiogenesis and tumour growth

✍ Scribed by Luca Mascitelli; Francesca Pezzetta; Mark R Goldstein

Book ID
116432293
Publisher
Elsevier Science
Year
2009
Tongue
English
Weight
84 KB
Volume
20
Category
Article
ISSN
0953-6205

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## Abstract We demonstrate that the 3‐hydroxy‐3‐methyl‐glutaryl‐coenzyme A (HMG‐CoA) reductase inhibitors atorvastatin and simvastatin enhance functional outcome and induce brain plasticity when administered after stroke to rats. With atorvastatin treatment initiated 1 day after stroke, animals exh