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STAT3 is constitutively activated and supports cell survival in association with survivin expression in gastric cancer cells

✍ Scribed by Kanda, Naoki; Seno, Hiroshi; Konda, Yoshitaka; Marusawa, Hiroyuki; Kanai, Masashi; Nakajima, Toshio; Kawashima, Tomoko; Nanakin, Apichart; Sawabu, Tateo; Uenoyama, Yoshito

Book ID: 110068680
Publisher: Nature Publishing Group
Year: 2004
Tongue: English
Weight: 344 KB
Volume: 23
Category: Article
ISSN: 0950-9232
DOI: 10.1038/sj.onc.1207606

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## Abstract Signal transducer and activator of transcription‐3 (STAT‐3) is constitutively activated in ovarian and endometrial cancers and is implicated in uncontrolled cell growth. Thus, its disruption could be an effective approach to control tumorigenesis. Curcumin is a dihydroxyphenolic compoun