Stable isotope liquid chromatography–tandem mass spectrometry assay for fatty acid amide hydrolase activity
✍ Scribed by Christin Rakers; Alexander A. Zoerner; Stefan Engeli; Sandor Batkai; Jens Jordan; Dimitrios Tsikas
- Book ID
- 113412315
- Publisher
- Elsevier Science
- Year
- 2012
- Tongue
- English
- Weight
- 666 KB
- Volume
- 421
- Category
- Article
- ISSN
- 0003-2697
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📜 SIMILAR VOLUMES
Isotope dilution gas chromatographic mass spectrometric assays were developed for the concentration of shortchain fatty acids and of lactate in plasma. The assays involve spiking the samples with 'Hand/or "C-labeled internal standards and direct derivatization with 2,4difluoroaniline, using 1,3-dicy
## Abstract __N__‐acetylaspartic acid (NAA) is a specific urinary marker for Canavan disease, an autosomal recessive leukodystrophy. We developed a ‘dilute and shoot’ stable isotope dilution liquid chromatography tandem mass spectrometry (LC‐MS/MS) method for determination of NAA in urine. Deuterat