✦ LIBER ✦

Stable Expression of Human Cytochrome P450 1B1 in V79 Chinese Hamster Cells and Metabolically Catalyzed DNA Adduct Formation of Dibenzo[ a , l ]pyrene

✍ Scribed by Luch, Andreas; Coffing, Stephanie L.; Tang, Yong M.; Schneider, Anneliese; Soballa, Volker; Greim, Helmut; Jefcoate, Colin R.; Seidel, Albrecht; Greenlee, William F.; Baird, William M.; Doehmer, Johannes

Book ID: 126880386
Publisher: American Chemical Society
Year: 1998
Tongue: English
Weight: 127 KB
Volume: 11
Category: Article
ISSN: 0893-228X
DOI: 10.1021/tx970236p

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Stable expression of human cytochrome P4

Stable expression of human cytochrome P450 2E1 in V79 Chinese hamster cells

✍ Wolfgang A. Schmalix; Martina Barrenscheen; Robert Landsiedel; Christine Janzows 📂 Article 📅 1995 🏛 Elsevier Science 🌐 English ⚖ 816 KB

Stable Expression of Rat Cytochrome P-45

Stable Expression of Rat Cytochrome P-450IIB1 cDNA in Chinese Hamster Cells (V79) and Metabolic Activation of Aflatoxin B1

✍ Johannes Doehmer, Satish Dogra, Thomas Friedberg, Solange Monier, Milton Adesnik 📂 Article 📅 1988 🏛 National Academy of Sciences 🌐 English ⚖ 938 KB

Stable Expression of Human Cytochrome P4

Stable Expression of Human Cytochrome P450 3A4 in Conjunction with Human NADPH-Cytochrome P450 Oxidoreductase in V79 Chinese Hamster Cells

✍ Anneliese Schneider; Wolfgang A. Schmalix; Vasanthi Siruguri; Els M. de Groene; 📂 Article 📅 1996 🏛 Elsevier Science 🌐 English ⚖ 258 KB

A quantitative comparison of dibenzo[a,l

A quantitative comparison of dibenzo[a,l]pyrene-DNA adduct formation by recombinant human cytochrome P450 microsomes

✍ Leon C. King; Linda Adams; Joycelyn Allison; Michael J. Kohan; Garret Nelson; Dh 📂 Article 📅 1999 🏛 John Wiley and Sons 🌐 English ⚖ 166 KB 👁 1 views

Dibenzo [a,l]pyrene (DB[a,l]P), an extremely potent environmental carcinogen, is metabolically activated in mammalian cells and microsomes through the fjord-region dihydrodiol, trans-DB[a,l]P-11,12-diol, to synand anti-DB[a,l]P-11,12-diol-13,14-epoxides (syn-and anti-DB[a,l]PDEs). The role of seven

Glutathione Conjugation and DNA Adduct F

Glutathione Conjugation and DNA Adduct Formation of Dibenzo[ a , l ]pyrene and Benzo[ a ]pyrene Diol Epoxides in V79 Cells Stably Expressing Different Human Glutathione Transferases

✍ Sundberg, Kathrin; Dreij, Kristian; Seidel, Albrecht; Jernström, Bengt 📂 Article 📅 2002 🏛 American Chemical Society 🌐 English ⚖ 168 KB

Chlorophyllin significantly reduces benz

Chlorophyllin significantly reduces benzo[a]pyrene-DNA adduct formation and alters cytochrome P450 1A1 and 1B1 expression and EROD activity in normal human mammary epithelial cells

✍ Channa Keshava; Rao L. Divi; Tracey L. Einem; Diana L. Richardson; Sarah L. Leon 📂 Article 📅 2009 🏛 John Wiley and Sons 🌐 English ⚖ 259 KB 👁 1 views

## Abstract We hypothesized that chlorophyllin (CHLN) would reduce benzo[__a__]pyrene‐DNA (BP‐DNA) adduct levels. Using normal human mammary epithelial cells (NHMECs) exposed to 4 μM BP for 24 hr in the presence or absence of 5 μM CHLN, we measured BP‐DNA adducts by chemiluminescence immunoassay (C