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Stabilization of β-Ribbon Structures in Peptides Using Disulfide Bonds

✍ Scribed by A.M. Aberle; H.K. Reddy; N.V. Heeb; K.P. Nambiar

Book ID
115574453
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
301 KB
Volume
200
Category
Article
ISSN
0006-291X

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The disulfide-bond forming reagent trans-[Pt(en) 2 Cl 2 ] 2+ cleanly, rapidly and quantitatively converts fully reduced a-conotoxin GI and a-conotoxin SI to their three disulfide bond-containing regioisomers in one-step in media of pH 3-7, enabling the convenient synthesis of the three isomers.