## Abstract The effectiveness of bifunctional alkylating nitrogen mustard compounds in chemotherapy is related to their ability to form DNA interβstrand crosslinks. Patients exposed to DNA interβstrand crosslinking (ICL) agents subsequently experience an elevated incidence of myelodysplastic syndro
β¦ LIBER β¦
Stabilization of nitrogen-mustard alkylations and inter-strand crosslinks in DNA by alkali
β Scribed by Kurt W. Kohn; Carlos L. Spears
- Book ID
- 115742600
- Publisher
- Elsevier Science
- Year
- 1967
- Weight
- 449 KB
- Volume
- 145
- Category
- Article
- ISSN
- 0005-2787
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Overexpression of GSTA2 protects against
β
Jingping Xie; Keith Shults; Leanne Flye; Fen Jiang; David R. Head; Robert C. Bri
π
Article
π
2005
π
John Wiley and Sons
π
English
β 326 KB
π 1 views
Inactivation by Nitrogen Mustard of Sing
β
Yamamoto, N.; Naito, T.
π
Article
π
1965
π
American Association for the Advancement of Scienc
π
English
β 512 KB
Alkylation of the dna of sensitive and r
β
T. A. Connors; J. A. Double
π
Article
π
1970
π
John Wiley and Sons
π
French
β 564 KB
## Abstract The concentration of ^3^Hβaniline mustard in two tumour lines has been measured and the level of binding of the drug to DNA followed for 48 hours after intraperitoneal injection. Although the two tumour lines differ a hundredβfold in their sensitivity to this alkylating agent, no good c
Observations on the in vivo alkylation o
β
R.J. Rutman; W.J. Steele; C.C. Price
π
Article
π
1961
π
Elsevier Science
π
English
β 250 KB
The relationship between cell-cycle dela
β
S.W. Dean; M. Fox
π
Article
π
1984
π
Elsevier Science
π
English
β 70 KB
Characterization of DNA-protein crosslin
β
Thomas, Cornelius B.; Kohn, Kurt W.; Bonner, William M.
π
Article
π
1978
π
American Chemical Society
π
English
β 632 KB