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Stabilization of iron regulatory protein 2, IRP2, by aluminum

✍ Scribed by Koji Yamanaka; Nagahiro Minato; Kazuhiro Iwai

Book ID
117111762
Publisher
Elsevier Science
Year
1999
Tongue
English
Weight
262 KB
Volume
462
Category
Article
ISSN
0014-5793

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## Abstract Central aspects of cellular iron metabolism are controlled by IRP1 and IRP2, which are ubiquitously expressed in mouse organs and cells. Total and constitutive deficiency of both IRPs causes embryonic lethality in the mouse. To bypass the early lethality and to study organ‐specific and/