✦ LIBER ✦

Stabilization and conformational isomerization of the cofactor during the catalysis in hydrolytic ALDHs

✍ Scribed by François Talfournier; Arnaud Pailot; Claire Stinès-Chaumeil; Guy Branlant

Book ID: 113517835
Publisher: Elsevier Science
Year: 2009
Tongue: English
Weight: 459 KB
Volume: 178
Category: Article
ISSN: 0009-2797
DOI: 10.1016/j.cbi.2008.10.045

No coin nor oath required. For personal study only.

📜 SIMILAR VOLUMES

Conformational isomerism in dihydropyran

Conformational isomerism in dihydropyran. Conjugative stabilization of the half-chair conformer

✍ C.Hackett Bushweller; James W. O'Neil 📂 Article 📅 1969 🏛 Elsevier Science 🌐 French ⚖ 167 KB

The various roles of the lone pair in the conformational dynamics and preferences of medium heterocycles are not clearly defined (11, although certain cases seem clear, e.g., the "E-axial effect" (2).

The Structure of a Designed Diiron(III)

The Structure of a Designed Diiron(III) Protein: Implications for Cofactor Stabilization and Catalysis

✍ Herschel Wade; Steven E. Stayrook; William F. DeGrado 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 345 KB 👁 3 views

The Structure of a Designed Diiron(III)

The Structure of a Designed Diiron(III) Protein: Implications for Cofactor Stabilization and Catalysis

✍ Herschel Wade; Steven E. Stayrook; William F. DeGrado 📂 Article 📅 2006 🏛 John Wiley and Sons 🌐 English ⚖ 346 KB

The crystal structure of phenol hydroxyl

The crystal structure of phenol hydroxylase in complex with FAD and phenol provides evidence for a concerted conformational change in the enzyme and its cofactor during catalysis

✍ Cristofer Enroth; Halina Neujahr; Gunter Schneider; Ylva Lindqvist 📂 Article 📅 1998 🏛 Elsevier Science 🌐 English ⚖ 1019 KB

The effect of cosolutes on the isomeriza

The effect of cosolutes on the isomerization of aspartic acid residues and conformational stability in a monoclonal antibody

✍ Aditya A. Wakankar; Jun Liu; David VanderVelde; Y. John Wang; Steven J. Shire; R 📂 Article 📅 2007 🏛 John Wiley and Sons 🌐 English ⚖ 187 KB 👁 1 views

The aspartate residue (Asp 32) located in the complementarity-determining region (CDR) of a recombinant humanized monoclonal antibody (MAb I) is highly susceptible to the isomerization reaction. The modification of Asp 32 residue due to the isomerization reaction results in a significant reduction i

Catalysis of disulfide bond formation an

Catalysis of disulfide bond formation and isomerization in the Escherichia coli periplasm

✍ Hitoshi Nakamoto; James C.A. Bardwell 📂 Article 📅 2004 🏛 Elsevier Science 🌐 English ⚖ 245 KB