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Stability of the lac repressor headpiece against thermal denaturation and tryptic hydrolysis

โœ Scribed by Manfred Schnarr; Jean-Claude Maurizot


Book ID
113264048
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
599 KB
Volume
702
Category
Article
ISSN
0167-4838

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Increasing and decreasing protein stabil
โœ Michael H. Hecht; Kathleen M. Hehir; Hillary C. M. Nelson; Julian M. Sturtevant; ๐Ÿ“‚ Article ๐Ÿ“… 1985 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 440 KB

The thermal denaturations of five revertant h repressors containing single amino acid substitutions in their N-terminal domains have been studied by differential scanning calorimetry. Two substitutions slightly decrease stability, and the remaining three render the protein more stable than wild type