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Stability of RNA hairpin loops: A6-Cm-U6

✍ Scribed by Olke C. Uhlenbeck; Philip N. Borer; Barbara Dengler; Ignacio Tinoco Jr

Book ID
118917366
Publisher
Elsevier Science
Year
1973
Tongue
English
Weight
974 KB
Volume
73
Category
Article
ISSN
0022-2836

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πŸ“œ SIMILAR VOLUMES

The stability of RNA hairpin loops conta
The stability of RNA hairpin loops containing A–U–G: An–U–G–Um
✍ Eric Wickstrom; Ignacio Tinoco Jr. πŸ“‚ Article πŸ“… 1974 πŸ› Wiley (John Wiley & Sons) 🌐 English βš– 875 KB

RNA oligomers with the sequence AJJ-G-Urn, n = 7-9, m = 5-10, have been synthesized and found to form hairpin loops in 21 mM or 101 mM Na+. The hairpin loops displayed melting temperatures 13'-29'C greater than that of the hairpin loop AsCs-U6 in the same solvent. The increased stability of these ha

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Characterisation and application of a bovine U6 promoter for expression of short hairpin RNAs
✍ Luke S Lambeth; Robert J Moore; Morley Muralitharan; Brian P Dalrymple; Sean McW πŸ“‚ Article πŸ“… 2005 πŸ› BioMed Central 🌐 English βš– 907 KB

## Background The use of small interfering RNA (siRNA) molecules in animals to achieve double-stranded RNA-mediated interference (RNAi) has recently emerged as a powerful method of sequence-specific gene knockdown. As DNA-based expression of short hairpin RNA (shRNA) for RNAi may offer some advanta

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