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Stability of poly(d,l-lactide-co-glycolide) and leuprolide acetate in in-situ forming drug delivery systems

✍ Scribed by W.Y. Dong; M. Körber; V. López Esguerra; R. Bodmeier


Book ID
113691307
Publisher
Elsevier Science
Year
2006
Tongue
English
Weight
622 KB
Volume
115
Category
Article
ISSN
0168-3659

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This study evaluated the in vivo biocompatibility and biodegradation behavior of a novel polypyrrole (PPy)/poly(D,L-lactide) (PDLLA) composite and PPy-coated poly(D,L-lactide-co-glycolide) membranes. Test membranes were implanted subcutaneously in rats for 3-120 days. The biocompatibility was assess