The incorporation of components with covalently attached polyethylene glycol (PEG) into nonviral vectors has been shown to prevent aggregation in serum and extend the circulating half-life of lipid/DNA complexes (lipoplexes) in vivo. The tendency of synthetic vectors to aggregate during processing a
Stability of lipid/DNA complexes during agitation and freeze–thawing
✍ Scribed by Thomas J. Anchordoquy; Lorinda G. Girouard; John F. Carpenter; David J. Kroll
- Book ID
- 109389112
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 96 KB
- Volume
- 87
- Category
- Article
- ISSN
- 0022-3549
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