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Stability of Enzymes and Proteins in Dried Glassy Systems: Effect of Simulated Sunlight Conditions

โœ Scribed by Luis Espinosa; Carolina Schebor; Norma S. Nudelman; Jorge Chirife

Book ID
109386976
Publisher
American Institute of Chemical Engineers
Year
2004
Tongue
English
Weight
98 KB
Volume
20
Category
Article
ISSN
8756-7938

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๐Ÿ“œ SIMILAR VOLUMES

Solid state chemistry of proteins: II. T
Solid state chemistry of proteins: II. The correlation of storage stability of freeze-dried human growth hormone (hGH) with structure and dynamics in the glassy solid
โœ Michael J. Pikal; Daniel Rigsbee; Michael L. Roy; Dawn Galreath; Karl J. Kovach; ๐Ÿ“‚ Article ๐Ÿ“… 2008 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 280 KB ๐Ÿ‘ 1 views

This research presents storage stability of human growth hormone, hGH, in lyophilized di-saccharide formulations. Stability via HPLC assay was assessed at 40 and 508C. Structure of the protein in the solids was assessed by infrared spectroscopy. Molecular mobility was characterized by structural rel