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Stability and apoptotic activity of recombinant human cytochrome c

✍ Scribed by Alina Olteanu; Chetan N Patel; Matthew M Dedmon; Scott Kennedy; Michael W Linhoff; Camille M Minder; Patrick R Potts; Mohanish Deshmukh; Gary J Pielak


Book ID
116287484
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
365 KB
Volume
312
Category
Article
ISSN
0006-291X

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Rapid determination of enzyme activities
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## Abstract Cytochrome P450 (CYP) substrates that yield fluorescent metabolites were used for rapid screening of drug metabolism activities of 13 recombinant human cytochromes P450, human liver microsomes and human hepatocytes. Reproducible results were obtained using a fluorescent plate reader (Cy