sst5 somatostatin receptor mRNA induction by mitogenic activation of human T-lymphocytes
✍ Scribed by Christelle El Ghamrawy; Chantal Rabourdin–Combe; Slavica Krantic
- Book ID
- 117409358
- Publisher
- Elsevier Science
- Year
- 1999
- Tongue
- English
- Weight
- 148 KB
- Volume
- 20
- Category
- Article
- ISSN
- 0196-9781
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
Neuropeptide somatostatin (SRIF) has been shown to modulate interleukin-2 (IL-2) secretion by mitogen-activated T cells. In this study, we further analyzed the transduction pathways underlying SRIF actions on human Jurkat T cells and compared SRIF signaling between nonactivated and mitogen-activated
The neuropeptide somatostatin (SRIF) modulates normal and leukemia T cell proliferation. However, neither molecular isotypes of receptors nor mechanisms involved in these somatostatin actions have been elucidated as yet. Here we show by using RT-PCR approach that mitogen-activated leukemia T cells (
## Rapid activation of ornithine decarboxylase by mitogenic (but not by nonmitogenic) ligands in human T lymphocytes* The T cell mitogens, concanavalin A and the monoclonal antibody OKT3, cause a rapid activation of ornithine decarboxylase (ODC) activity in human T lymphocytes, maximal within 10 m