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SSCP Screening of the Dihydropyrimidine Dehydrogenase Gene Polymorphisms of the Japanese Population Using a Semi-automated Electrophoresis Unit

✍ Scribed by Yoshihiro Okamoto; Akihito Ueta; Satoshi Sumi; Tetsuya Ito; Yumiko Okubo; Yuki Jose; Akiko Ninomiya; Hajime Togari; Mikio Nishida


Publisher
Springer
Year
2007
Tongue
English
Weight
266 KB
Volume
45
Category
Article
ISSN
0006-2928

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The length polymorphism in the 5′ flanki
✍ Norio Takahashi; Keiko Hiyama; Mieko Kodaira; Chiyoko Satoh 📂 Article 📅 1991 🏛 Springer 🌐 English ⚖ 266 KB

The ATTTT repeat polymorphism located approximately 1,400 base pairs (bp) upstream from the beta-globin structural gene was analyzed by denaturing gradient gel electrophoresis (DGGE) of RNA:DNA duplexes. A study of 81 unrelated Japanese from Hiroshima revealed a sequence heteromorphism in this site.