SSCP analysis of pig mitochondrial DNA D-loop region polymorphism
β Scribed by K Takeda; A Onishi; N Ishida; K Kawakami; M Komatsu; S Inumaru
- Book ID
- 114706264
- Publisher
- John Wiley and Sons
- Year
- 2009
- Tongue
- English
- Weight
- 557 KB
- Volume
- 26
- Category
- Article
- ISSN
- 0268-9146
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Phylogenetic relationships among Asian and European pig breeds were assessed using 1036βbp of mitochondrial DNA (mtDNA) Dβloop sequences. An unweighted pairβgroup method with arithmetic mean (UPGMA) tree was constructed on the basis of maximum likelihood distances using sequences determined for thre
A number of mitochondrial (mt) point mutations have been associated with inherited disorders. These pathogenic mutations are usually heteroplasmic. Here we describe the identification of three heteroplasmic mtDNA point mutations using the techniques of single stranded conformation polymorphism (SSCP