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Detection of aberrant alleles in the D-loop region of equine mitochondrial DNA by single-strand conformation polymorphism (SSCP) analysis

โœ Scribed by N Ishida; T Hirano; H Mukoyama


Book ID
114706071
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
144 KB
Volume
25
Category
Article
ISSN
0268-9146

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The detection of mitochondrial DNA mutat
โœ Andrew Wyn Thomas; Ruth Morgan; Mary Sweeney; Alan Rees; John Alcolado ๐Ÿ“‚ Article ๐Ÿ“… 1994 ๐Ÿ› Springer ๐ŸŒ English โš– 347 KB

A number of mitochondrial (mt) point mutations have been associated with inherited disorders. These pathogenic mutations are usually heteroplasmic. Here we describe the identification of three heteroplasmic mtDNA point mutations using the techniques of single stranded conformation polymorphism (SSCP