The detection of mitochondrial DNA mutat
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Andrew Wyn Thomas; Ruth Morgan; Mary Sweeney; Alan Rees; John Alcolado
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Article
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1994
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Springer
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English
โ 347 KB
A number of mitochondrial (mt) point mutations have been associated with inherited disorders. These pathogenic mutations are usually heteroplasmic. Here we describe the identification of three heteroplasmic mtDNA point mutations using the techniques of single stranded conformation polymorphism (SSCP