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SRN1 reactions in imidazo [1, 2-a] pyridine series

✍ Scribed by Patrice Vanelle; José Maldonado; Nasser Madadi; Alain Gueiffier; Jean-Claude Teulade; Jean-Pierre Chapat; Michel P. Crozet

Publisher
Elsevier Science
Year
1990
Tongue
French
Weight
239 KB
Volume
31
Category
Article
ISSN
0040-4039

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The synthesis of imidazo [1,2-a]pyridine and imidazo[1,2-a]pyrimidine derivatives by condensation between an a-bromoketone bound to solid support and various 2-aminopyridine or 2-aminopyrimidine derivatives was described. Either an acid labile linker or a base labile linker was used in this study.