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SREBP-1c Transcription Factor and Lipid Homeostasis: Clinical Perspective

✍ Scribed by Ferré, P.; Foufelle, F.

Book ID
119984733
Publisher
S. Karger AG
Year
2007
Tongue
English
Weight
346 KB
Volume
68
Category
Article
ISSN
1663-2818

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SREBP-1c Transcription Factor and Lipid
SREBP-1c Transcription Factor and Lipid Homeostasis: Clinical Perspective
✍ Ferré, P.; Foufelle, F. 📂 Article 📅 2007 🏛 S. Karger AG 🌐 English ⚖ 346 KB

Insulin has long-term effects on glucose and lipid metabolism through its control on the expression of specific genes. In insulin sensitive tissues and particularly in the liver, the transcription factor sterol regulatory element binding protein-1c (SREBP-1c) transduces the insulin signal. SREBP-1c