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Transcription factor 7–like 2 polymorphism modulates glucose and lipid homeostasis, adipokine profile, and hepatocyte apoptosis in NASH

✍ Scribed by Giovanni Musso; Roberto Gambino; Giovanni Pacini; Gianfranco Pagano; Marilena Durazzo; Maurizio Cassader

Book ID: 102242005
Publisher: John Wiley and Sons
Year: 2008
Tongue: English
Weight: 304 KB
Volume: 49
Category: Article
ISSN: 0270-9139
DOI: 10.1002/hep.22659

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## Abstract ## Background Although variants in the transcription factor 7‐like 2 (__TCF7L2__) gene are consistently associated with impaired fasting glucose (IFG) in Caucasians, data from large population‐based studies of African Americans are lacking. Moreover, few studies have investigated the e