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Squaramide-Catalyzed Enantioselective Michael Addition of Diphenyl Phosphite to Nitroalkenes

✍ Scribed by Ye Zhu; Jeremiah P. Malerich; Viresh H. Rawal


Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
295 KB
Volume
122
Category
Article
ISSN
0044-8249

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✍ Ana Alcaine; Eugenia Marques-Lopez; Pedro Merino; Tomas Tejero; Raquel P. Herrer 📂 Article 📅 2011 🏛 John Wiley and Sons ⚖ 28 KB

## Abstract A variety of enantioenriched β‐nitrophosphonates (III) is readily obtained by asymmetric Michael addition of diphenylphosphite (II) to nitroolefins (I) in the presence of a bifunctional amine—thiourea organocatalyst.