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Squalene inhibits sodium arsenite-induced sister chromatid exchanges and micronuclei in Chinese hamster ovary-K1 cells

โœ Scribed by Shyh-Rong Fan; I-Ching Ho; Fenny Lai-Fun Yeoh; Chi-Jen Lin; Te-Chang Lee


Book ID
117331678
Publisher
Elsevier Science
Year
1996
Tongue
English
Weight
382 KB
Volume
368
Category
Article
ISSN
0165-1218

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Culture of cells in high exogenous levels (greater than 10(-4) M) of bromodeoxyuridine (BrdUrd) or thymidine will increase the baseline sister chromatid exchange (SCE) frequency. The effect is thought to be related to the balance of the DNA precursors thymidine and deoxycytidine. Exogenous addition