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Micrococcus luteus UV-endonuclease-sensitive sites and sister-chromatid exchanges in Chinese hamster ovary cells

โœ Scribed by R.J. Reynolds; A.T. Natarajan; P.H.M. Lohman


Book ID
113249710
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
229 KB
Volume
64
Category
Article
ISSN
0165-1161

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Culture of cells in high exogenous levels (greater than 10(-4) M) of bromodeoxyuridine (BrdUrd) or thymidine will increase the baseline sister chromatid exchange (SCE) frequency. The effect is thought to be related to the balance of the DNA precursors thymidine and deoxycytidine. Exogenous addition