Spray granulation for drug formulation
โ Scribed by Loh, Zhi Hui; Er, Dawn ZL; Chan, Lai Wah; Liew, Celine V; Heng, Paul WS
- Book ID
- 120245562
- Publisher
- Informa plc
- Year
- 2011
- Tongue
- English
- Weight
- 427 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1742-5247
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๐ SIMILAR VOLUMES
Aplaviroc 200 mg tablets were made by a high shear wet granulation process. A formulation and process DOE were carried out to define formulation and process parameters at pilot scale in GSKs R&D facility. During the scale up, several batches made at the production facility dissolved slower than the
A spray-drying technique has been investigated which provides a free-flowing powder with decreased dissolution rate for the medicinal agent when compressed into tablets. The fine powder (16150 p ) obtained by this process has proved to possess excellent drug distribution and when tableted offers goo