Spontaneous microdeletions and microinsertions in a transgenic mouse mutation detection system: analysis of age, tissue, and sequence specificity

Other transgenic mutation assays: Tissue

Other transgenic mutation assays: Tissue specificity of spontaneous point mutations in λsupF transgenic mice

✍ Eric G. Leach; Latha Narayanan; Pamela A. Havre; Edward J. Gunther; Toni M. Yeas 📂 Article 📅 1996 🏛 John Wiley and Sons 🌐 English ⚖ 498 KB 👁 2 views

Transgenic mice carrying multiple copies of a recoverable h phage shuttle vector carrying the supF mutation reporter gene (hsupF) were constructed for the purpose of studying mutagenesis in a whole animal. Spontaneous mutations in rescued supF target genes from mouse liver and skin were analyzed. Th