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Spontaneous lesions of nasal cavity in aging F344 rats and BDF1 mice

โœ Scribed by K. Nagano; T. Katagiri; S. Aiso; H. Senoh; Y. Sakura; T. Takeuchi

Book ID
114305786
Publisher
Elsevier Science
Year
1997
Tongue
English
Weight
775 KB
Volume
49
Category
Article
ISSN
0940-2993

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Glycidol, a simple aliphatic epoxide, was administered by gavage in water to groups of male and female F344/N rats and B6C3F1 mice. Rats received 0, 37.5 or 75 mg kg-' and mice received 0, 25 or 50 mg kg-' daily, 5 days per week for 2 years. Exposure to glycidol was associated with dose-related incr