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Spontaneous increase of DNA turnover in murine systemic lupus erythematosus

✍ Scribed by Dov T. Golan; Yves Borel

Publisher
John Wiley and Sons
Year
1983
Tongue
English
Weight
434 KB
Volume
13
Category
Article
ISSN
0014-2980

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## Abstract ## Objective Proteolytic autoantigen cleavage by the serine protease granzyme B has been implicated in the development of systemic autoimmune disease; however, there has been no conclusive demonstration of a pathogenic role for granzyme B in autoimmunity. In this study, we evaluated th