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Spontaneous Immortalization of Clinically Normal Colon-Derived Fibroblasts from a Familial Adenomatous Polyposis Patient

โœ Scribed by Forsyth, Nicholas R.; Morales, Carmela P.; Damle, Shirish; Boman, Bruce; Wright, Woodring E.; Kopelovich, Levy; Shay, Jerry W.


Book ID
122277812
Publisher
Neoplasia Press
Year
2004
Tongue
English
Weight
397 KB
Volume
6
Category
Article
ISSN
1522-8002

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Loss of normal allele of the APC gene in
โœ Madoka Seki; Kiyoko Tanaka; Rei Kikuchi-Yanoshita; Motoko Konishi; Hiroyuki Fuku ๐Ÿ“‚ Article ๐Ÿ“… 1992 ๐Ÿ› Springer ๐ŸŒ English โš– 272 KB

Endocrine neoplasms have been reported occasionally in patients with familial adenomatous polyposis (FAP). An adrenocorotical carcinoma was studied in a patient with a family history of FAP. Loss of heterozygosity (LOH) in the region close to the adenomatous polyposis coli (APC) gene was detected in