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Spontaneous and mitomycin-C induced sister-chromatid exchanges: Comparison of in vivo and in vitro systems

โœ Scribed by David Kram; Edward L. Schneider; Gerhard C. Senula; Yoshifumi Nakanishi

Book ID
113191532
Publisher
Elsevier Science
Year
1979
Tongue
English
Weight
514 KB
Volume
60
Category
Article
ISSN
0027-5107

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Reduced frequencies of Mitomycin-C induc
Reduced frequencies of Mitomycin-C induced sister chromatid exchanges in AKR Mice
โœ David Kram; Edward L. Schneider ๐Ÿ“‚ Article ๐Ÿ“… 1978 ๐Ÿ› Springer ๐ŸŒ English โš– 333 KB

The frequencies of base-line and Mitomycin-C (MMC) induced sister chromatid exchanges (SCE) were surveyed in four inbred strains of mice. In contrast to the C57Bl/6J, CBA/J, and A/J strains where frequencies of SCE increased linearly with increasing dose of MMC, levels of SCE were significantly lowe