✦ LIBER ✦

Spontaneous and induced interferon production by peripheral blood leucocytes from control population and patients with herpes genitalis

✍ Scribed by D. Lannello; M. W. Taylor; K. H. Fife; L. Chen

Book ID: 102905658
Publisher: John Wiley and Sons
Year: 1987
Tongue: English
Weight: 544 KB
Volume: 22
Category: Article
ISSN: 0146-6615
DOI: 10.1002/jmv.1890220105

No coin nor oath required. For personal study only.

✦ Synopsis

The spontaneous and PHA induced levels of interferon were measured in peripheral blood leucocyte cultures of twenty-eight individuals diagnosed as positive for herpes genitalis, and in a group of control subjects. As reported by Cunningham and Merigan [1983] for herpes labialis, leucocytes from individuals with herpes genitalis produced low levels of interferon spontaneously; however, similar results were found for individuals within the control population. No statistically significant difference could be found for PHA induced interferon levels, antigen induced interferon levels, or helper/suppressor cell ratios between the herpes genitalis population and control population. Our results indicate that interferon does not play a major role in the latency or recurrence of herpes genitalis.

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