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Split hand and foot malformation: ultrasound detection in the first trimester

✍ Scribed by Dr O. Lapaire; M. Schiesser; R. Peukert; W. Holzgreve; S. Tercanli

Book ID
114435354
Publisher
John Wiley and Sons
Year
2002
Tongue
English
Weight
48 KB
Volume
20
Category
Article
ISSN
0960-7692

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## Abstract The split hand/foot malformation is a developmental defect of the extremities resulting from errors in the initiation and maintenance of the apical ectodermal ridge. The phenotype is genetically heterogeneous, and it can be identified either as an isolated phenotypic manifestation or as