Spliceosome-mediated RNA trans-splicing as a tool for gene therapy
β Scribed by Garcia-Blanco, Mariano A.; Mitchell, Lloyd G.; Puttaraju, M.; Jamison, Sharon F.; Mansfield, S. Gary
- Book ID
- 109827004
- Publisher
- Nature Publishing Group
- Year
- 1999
- Tongue
- English
- Weight
- 227 KB
- Volume
- 17
- Category
- Article
- ISSN
- 1087-0156
- DOI
- 10.1038/6986
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
Interleukin 17 (IL-17) is an essential proinflammatory T-cell derived cytokine with various biological actions. IL-17 was found to have a pivotal role in microbial host defense by interconnecting lymphoid and myeloid host defense. It also acts as a stimulatory hematopoietic cytokine by expanding mye
## Abstract ## Background Congenital erythropoietic porphyria (CEP) is a severe autosomal recessive disorder characterized by a deficiency in uroporphyrinogen III synthase (UROS), the fourth enzyme of the heme biosynthetic pathway. We recently demonstrated the definitive cure of a murine model of