Splenic tuberculosis in a patient with Crohn's disease on infliximab: Case report
โ Scribed by Maria Cappello; Claudia Randazzo; Giulia Rizzuto; Celestino Bonura; Gaetano Di Vita; Massimo Galia
- Publisher
- John Wiley and Sons
- Year
- 2010
- Tongue
- English
- Weight
- 255 KB
- Volume
- 16
- Category
- Article
- ISSN
- 1078-0998
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โฆ Synopsis
FIGURE 1. MRI of the spleen. a: T1-weighted image on dynamic contrast-enhancement (axial). b: T1-weighted image on dynamic contrast-enhancement (coronal).
๐ SIMILAR VOLUMES
The use of tumor necrosis factor a (TNFa) inhibitors such as infliximab, etanercept, and adalimumab for various autoimmune diseases, including Crohn's disease (CD) and ulcerative colitis (UC), has increased in the past few years. While associated with symptomatic relief in many patients, the use of
Background: Under experimental chronic inflammation, tumor necrosis factor (TNF)-โฃ plays a role in damaging spleen marginal zone. This latter has a crucial function in mounting B cell-dependent immune responses against infections by encapsulated bacteria. In Crohn's disease (CD), a chronic inflammat