Splenic T and B lymphocytes and their mitogenic response in untreated Hodgkin's disease
β Scribed by Tin Han; Jun Minowada; Vadakkencheri Subramanian; Maurice Barcos; Untae Kim
- Publisher
- John Wiley and Sons
- Year
- 1980
- Tongue
- English
- Weight
- 756 KB
- Volume
- 45
- Category
- Article
- ISSN
- 0008-543X
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π SIMILAR VOLUMES
The prevalence of complement dependent, cold-reactive lymphocytotoxic serum factors (LT) was studied in 80 untreated patients with Hodgkin's disease by a microcytotoxicity assay. Sera from 24 patients (30%) contained LT as judged from at least 50% lysis of lymphocytes from 16 of 23 randomly selected
Blood lymphocytes from 20 untreated patients with Hodgkin's disease were compared with those of 20 untreated patients with non-Hodgkin's lymphoma with regard to the responsiveness of the cells to PHA and ConA following exposure to varying doses of ionizing radiation in vitro. Lymphocytes from 19 of
Blood lymphocytes from 10 untreated patients with active Hodgkin's disease were compared with those of 10 cured patients with regard to the responsiveness of the cells to PHA and Con A following in vitro irradiation. Lymphocytes of patients remaining in long-term remission exhibited the same pattern