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Splenic rupture in a patient with acute myeloid leukemia undergoing peripheral blood stem cell transplantation

✍ Scribed by C. Kasper; L. Jones; Y. Fujita; G. R. Morgenstern; J. H. Scarffe; J. Chang


Publisher
Springer
Year
1999
Tongue
English
Weight
42 KB
Volume
78
Category
Article
ISSN
0939-5555

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## Abstract Splenic rupture (SR) is a rare adverse event observed in patients treated with G‐CSF as a peripheral hematopoietic stem cell (PHSC) mobilizing agent, mostly in myeloma multiple and amiloidosis; to date, to our knowledge, it has not been previously described in plasma‐cell leukemia (PCL)

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Although a second stem cell transplantation (SCT) can be used as salvage therapy in patients with relapsing leukemia after SCT, most of these patients have a poor outcome. We tried clinical vaccination using monocyte-derived dendritic cells (DCs) pulsed with leukemic lysates to treat relapsing acute