Spirothiazolo[4′,2]- and Thiazolo[3,4-a]quinoxalines Based on 3-(α-Bromoethyl)quinoxalin-2-ones and Thiourea.
✍ Scribed by A. A. Kalinin; O. G. Isaikina; V. A. Mamedov
- Publisher
- John Wiley and Sons
- Year
- 2005
- Weight
- 18 KB
- Volume
- 36
- Category
- Article
- ISSN
- 0931-7597
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## Abstract Some 1,2,4‐triazolo[4,3‐__a__]quinoxalines 1–10, and 1,2,4‐triazino[4,3‐__a__]quinoxalines 11–12 were prepared and biologically evaluated for their binding at the benzodiazepine receptor (BZR) in rat cortical membranes. The BZR affinity of 1–10 demonstrates that the presence of a proton