## ABSTRACT The case of a 70βyearβold white man with a 10βyear history of penile lichen sclerosus (LS) who developed microinvasive squamous cell carcinoma on LS is described. A high incidence of penile cancer arising on genital LS has recently been observed. The authors stress the importance of an
Spindle and pseudoglandular squamous cell carcinoma arising in lichen sclerosus of the vulva
β Scribed by Cockayne; Shah; Slater; Harrington
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 353 KB
- Volume
- 138
- Category
- Article
- ISSN
- 0007-0963
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β¦ Synopsis
An 83-year-old woman presented with a vulval mass. Radical vulvectomy was performed and histology showed a unique mixed picture of spindle, pseudoglandular and classical squamous cell carcinoma arising in vulval lichen sclerosus.
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## Abstract A 61βyear-old woman, who was known to have HaileyβHailey disease, presented with increasing vulval soreness. Biopsy showed vulval intraepithelial neoplasia (VIN) 3 and subsequent histology from a vulvectomy specimen showed extensive VIN with early invasive squamous cell carcinoma. This
## Background: The objective of the study was to evaluate the pathogenetic and prognostic value of p53 protein expression in squamous cell carcinoma of the vulva. ## Methods: The clinical data in charts of 167 patients with international federation of gynecology and obstetrics (figo) stages i-iii