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Sphingosine 1-phosphate: synthesis and release

✍ Scribed by Yutaka Yatomi; Yukio Ozaki; Tsukasa Ohmori; Yasuyuki Igarashi

Book ID
114100702
Publisher
Elsevier Science
Year
2001
Tongue
English
Weight
266 KB
Volume
64
Category
Article
ISSN
0090-6980

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## Abstract Readily available D‐__erythro__‐azidosphingosine is transformed into 3‐__O__‐silyl‐protected derivative 6. Reduction of the azido group afforded 3‐__O__‐silyl‐protected sphingosine 7 which was either converted into __N__‐Fmoc‐protected derivative 8 or via N‐acylation into ceramide deriv