Sphingosine-1-phosphate stimulates human caco-2 intestinal epithelial proliferation and activates ERK and p38 by independent mechanisms.
✍ Scribed by Wei Li; Bauer E Sumpio; Marc D Basson
- Book ID
- 114353960
- Publisher
- Elsevier Science
- Year
- 2000
- Tongue
- English
- Weight
- 164 KB
- Volume
- 191
- Category
- Article
- ISSN
- 1072-7515
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The Ca^2+^‐modulated protein of the EF‐hand type, S100B, was shown to inhibit rat L6 myoblast differentiation and myotube formation by interacting with a high affinity with an unidentified receptor (Sorci et al., 2003). We show here that S100B independently inhibits the MKK6‐p38 MAPK pa
To investigate the mechanisms responsible for survival and apoptosis/anoikis in normal human intestinal epithelial crypt cells, we analyzed the roles of various signaling pathways and cell adhesion on the expression of six Bcl-2 homologs (Bcl-2, Bcl-XL, Mcl-1, Bax, Bak, Bad) in the well established
## Abstract We have shown that the bacterial iron chelator, deferoxamine (DFO), triggers inflammatory signals including the production of CXC chemokine IL‐8, in human intestinal epithelial cells (IECs) by activating the ERK1/2 and p38 kinase pathways. In this study we investigated the mechanisms in
## Abstract Bone loss that causes aseptic loosening of orthopedic implants is initiated by pro‐inflammatory cytokines produced by macrophages in response to implant‐derived wear particles. MAPK and NF‐κB signaling pathways are activated by the particles; however, it is not clear which of the signal