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Sphingosine-1-phosphate is a mediator of TNF-α action on the Na+/K+ ATPase in HepG2 cells

✍ Scribed by Zeina Dakroub; Sawsan Ibrahim Kreydiyyeh


Book ID
112120140
Publisher
John Wiley and Sons
Year
2012
Tongue
English
Weight
443 KB
Volume
113
Category
Article
ISSN
0730-2312

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## Abstract An inhibition of the Na^+^/K^+^ATPase was previously shown to accompany and potentiate apoptosis in different experimental models. Since TNF‐α is known to be a pro and anti‐apoptotic cytokine, this work was undertaken to study the effect of TNF‐α on the Na^+^/K^+^ATPase in HepG2 cells a