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Signaling pathway underlying the up-regulatory effect of TNF-α on the Na+/K+ ATPase in HepG2 cells

✍ Scribed by Ari Kassardjian; Zeina Dakroub; Ola El Zein; Sawsan Ibrahim Kreydiyyeh


Book ID
116399395
Publisher
Elsevier Science
Year
2010
Tongue
English
Weight
494 KB
Volume
49
Category
Article
ISSN
1043-4666

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## Abstract An inhibition of the Na^+^/K^+^ATPase was previously shown to accompany and potentiate apoptosis in different experimental models. Since TNF‐α is known to be a pro and anti‐apoptotic cytokine, this work was undertaken to study the effect of TNF‐α on the Na^+^/K^+^ATPase in HepG2 cells a