Sphingosine-1-phosphate and sphingosylphosphorylcholine: two of a kind?
β Scribed by Astrid E Alewijnse; Martin C Michel
- Book ID
- 110009007
- Publisher
- Nature Publishing Group
- Year
- 2006
- Tongue
- English
- Weight
- 78 KB
- Volume
- 147
- Category
- Article
- ISSN
- 0007-1188
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π SIMILAR VOLUMES
A novel regioselective synthesis of D-erythro -sphingosine 1-phosphate and D-erythro -ceramide 1-phosphate is described. The synthesis is based upon (1) in situ oxidative phosphorylation of the primary hydroxyl group in N-Boc-D-erythro-sphingosine utilizing trimethyl phosphite and carbon tetrabromid
## Abstract The (lyso)phospholipid mediators sphingosineβ1βphosphate (S1P), lysophosphatidic acid (LPA), sphingosylphosphorylcholine (SPC), and phosphatidic acid (PA) regulate diverse cellular responses such as proliferation, survival and death, cytoskeletal rearrangements, cell motility, and diffe