Signal transduction underlying the vascular effects of sphingosine 1-phosphate and sphingosylphosphorylcholine
β Scribed by Denise G. Hemmings
- Book ID
- 105876556
- Publisher
- Springer-Verlag
- Year
- 2006
- Tongue
- English
- Weight
- 193 KB
- Volume
- 373
- Category
- Article
- ISSN
- 0028-1298
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In Xenopus oocytes, both sphingosine-1-phosphate (S1P) and lysophosphatidic acid (LPA) activate Ca2+-dependent oscillatory Cl- currents by acting through membrane-bound receptors. External application of 50 microM S1P elicited a long-lasting oscillatory current that continued over 30 min from the be