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Sphingosine 1-phosphate and cell migration: resistance to angiogenesis inhibitors

✍ Scribed by Takeshi Morii; Lawrence Weissbach

Book ID
116287153
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
259 KB
Volume
310
Category
Article
ISSN
0006-291X

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## Abstract Sphingosine 1‐phosphate (S1P) and vascular endothelial growth factor (VEGF) are two inflammatory mediators capable of promoting endothelial cell (EC) migration and angiogenesis. As VEGF inflammatory effect is mediated by the synthesis of endothelial platelet‐activating factor (PAF) whic